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MEMANTINE 10MG COAT TBL N28

Attention: Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for treating a health problem or disease, or prescribing any medication. iDrugs24.com is not responsible for any damage to your health as the result of self treatment.

# On 2024-Mar-28
MEMANTINE-drug/medicine -tablets aproximate price on "MEMANTINE 10MG COAT TBL N28" in Riga city, Latvia is:
  • 19.54€  21.13$  16.76£  2257Rub  224.8SEK  84PLN  77.34₪ 


Maximum allowed state defined price ( from ZVA webpage) Euro:State defined maximum allowed price indicated on the picture on drug/medicine -tablets  MEMANTINE 10MG COAT TBL N28     Recheck

ATC codeN06DX01 

Active substances: Memantinum

 


Vendor, principal: Ratiopharm

 Prescription drug (℞) 

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* This table was compiled fully automatically, independently from any advertisers, transparently and without any modification relaying the open offers available on the mentioned dates.Only the distribution of over-the-counter remedies through the website is permitted in Latvia in accordance with national laws and regulations.

EUROPEAN MEDICINES AGENCY

SCIENCE MEDICINES HEALTH

EMEA/H/C/002671

EPAR summary for the public

Memantine ratiopharm

memantine hydrochloride

This is a summary of the European public assessment report (EPAR) for Memantine ratiopharm. It explains how the Agency assessed the medicine to recommend its authorisation in the EU and its conditions of use. It is not intended to provide practical advice on how to use Memantine ratiopharm.

For practical information about using Memantine ratiopharm, patients should read the package leaflet or contact their doctor or pharmacist.

What is Memantine ratiopharm and what is it used for?

Memantine ratiopharm is a medicine that contains the active substance memantine hydrochloride. It is used to treat patients with moderate to severe Alzheimer's disease. Alzheimer's disease is a type of dementia (a brain disorder) that gradually affects memory, intellectual ability and behaviour.

Memantine ratiopharm is a generic medicine'. This means that Memantine ratiopharm is similar to a Reference medicine' already authorised in the European Union (EU) called Ebixa. For more information on generic medicines, see the question-and-answer document here.

How is Memantine ratiopharm used?

Memantine ratiopharm is available as tablets (5 mg, 10 mg, 15 mg and 20 mg) and can only be obtained with a prescription.

Treatment should be started and supervised by a doctor who has experience in the diagnosis and treatment of Alzheimer's disease. Treatment should only be started if a caregiver is available who will regularly monitor the use of Memantine ratiopharm by the patient.

Memantine ratiopharm should be given once a day at the same time every day. To prevent side effects, the dose of Memantine ratiopharm is gradually increased over the first three weeks of treatment: during the first week, the dose is 5 mg; in the second week, it is 10 mg; and during the third week, it is 15 mg. From week four onwards, the recommended maintenance dose is 20 mg once a day. The tolerance and dose should be assessed within three months after starting treatment, and

An agency of the European Union

WC5EN00144582

7 Westferry Circus Canary Wharf London E14 4HB United Kingdom Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8416 E-mail [email protected] Website www.ema.europa.eu

© European Medicines Agency, 2013. Reproduction is authorised provided the source is acknowledged.

from then on the benefits of continuing treatment with Memantine ratiopharm should be re-assessed on a regular basis. The dose may need to be reduced in patients who have moderate or severe problems with their kidneys.

For more information, see the package leaflet.

How does Memantine ratiopharm work?

The active substance in Memantine ratiopharm, memantine hydrochloride, is an antidementia medicine. The cause of Alzheimer's disease is unknown, but memory loss in the disease is believed to be due to a disturbance of message signals in the brain.

Memantine works by blocking special types of receptor called NMDA receptors, to which the neurotransmitter glutamate normally attaches. Neurotransmitters are chemicals in the nervous system that allow nerve cells to communicate with one another. Changes in the way glutamate transmits signals within the brain have been linked to the memory loss seen in Alzheimer's disease. In addition, overstimulation of the NMDA receptors can result in cell damage or death. By blocking NMDA receptors, memantine improves the transmission of signals in the brain and reduces the symptoms of Alzheimer's disease.

How has Memantine ratiopharm been studied?

Because Memantine ratiopharm is a generic medicine, studies in patients have been limited to tests to determine that it is bioequivalent to the reference medicine, Ebixa. Two medicines are bioequivalent when they produce the same levels of the active substance in the body.

What are the benefits and risks of Memantine ratiopharm?

Because Memantine ratiopharm is a generic medicine and is bioequivalent to the reference medicine, its benefits and risks are taken as being the same as the reference medicine's.

Why is Memantine ratiopharm approved?

The Agency's Committee for Medicinal Products for Human Use (CHMP) concluded that, in accordance with EU requirements, Memantine ratiopharm has been shown to have comparable quality and to be bioequivalent to Ebixa. Therefore, the CHMP's view was that, as for Ebixa, the benefit outweighs the identified risk. The Committee recommended that Memantine ratiopharm be approved for use in the EU.

What measures are being taken to ensure the safe and effective use of Memantine ratiopharm?

Safety information has been included in the summary of product characteristics and the package leaflet for Memantine ratiopharm, including the appropriate precautions to be followed by healthcare professionals and patients.

Other information about Memantine ratiopharm

The European Commission granted a marketing authorisation valid throughout the European Union for Memantine ratiopharm on 13 June 2013.

The full EPAR for Memantine ratiopharm can be found on the Agency's website: ema.europa.eu/Find medicine/Human medicines/European public assessment reports. For more information about

treatment with Memantine ratiopharm, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist.

The full EPAR for the reference medicine can also be found on the Agency's website.

This summary was last updated in June 2013.

Memantine ratiopharm

EMA/200878/2013

Page 3/3



 Instruction , annotation source: The European Medicines Agency


[*1]

DDD. Information source: WHO Collaborating Centre for Drug Statistics Methodology. Norwegian Institute of Public Health


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