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RAMIPRIL BILLEV 2.5MG TBL N30

Attention: Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for treating a health problem or disease, or prescribing any medication. iDrugs24.com is not responsible for any damage to your health as the result of self treatment.

# On 2024-Mar-29
RAMIPRIL-BILLEV-drug/medicine -tablets aproximate price on "RAMIPRIL BILLEV 2.5MG TBL N30 " in Riga city, Latvia is:
  • 3.39€  3.66$  2.9£  391Rub  39.1SEK  15PLN  13.49₪ 


Maximum allowed state defined price ( from ZVA webpage) Euro:State defined maximum allowed price indicated on the picture on drug/medicine -tablets  RAMIPRIL BILLEV 2.5MG TBL N30     Recheck

ATC codeC09AA05 

Active substances: Ramiprilum

 


Vendor, principal: Krka
RAMIPRIL BILLEV 2.5MG TBL N30 is compensated medicine in Latvia. 

 Prescription drug (℞) 

* This table was compiled fully automatically, independently from any advertisers, transparently and without any modification relaying the open offers available on the mentioned dates.Only the distribution of over-the-counter remedies through the website is permitted in Latvia in accordance with national laws and regulations.
 .

RAMIPRIL ACTAVIS 5MG N28

Package leaflet: Information for the user

RAMIPRIL ACTAVIS 2.5 mg tablets RAMIPRIL ACTAVIS 5 mg tablets RAMIPRIL ACTAVIS 10 mg tablets
Ramipril

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

-   Keep this leaflet. You may need to read it again.
-   If you have any further questions, ask your doctor, pharmacist or nurse.
-   This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
-   If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet

1.   What RAMIPRIL ACTAVIS is and what it is used for
2.   What you need to know before you take RAMIPRIL ACTAVIS
3.   How to take RAMIPRIL ACTAVIS
4.   Possible side effects
5.   How to store RAMIPRIL ACTAVIS
6.   Contents of the pack and other information

1.   What RAMIPRIL ACTAVIS is and what it is used for

RAMIPRIL ACTAVIS contains a medicine called ramipril. This belongs to a group of medicines called ACE inhibitors (Angiotensin Converting Enzyme Inhibitors).
RAMIPRIL ACTAVIS works by:
•   Decreasing your body’s production of substances that could raise your blood pressure
•   Making your blood vessels relax and widen
•   Making it easier for your heart to pump blood around your body.
RAMIPRIL ACTAVIS can be used:
•   To treat high blood pressure (hypertension)
•   To reduce the risk of you having a heart attack or stroke
•   To reduce the risk or delay the worsening of kidney problems (whether or not you have diabetes)
•   To treat your heart when it cannot pump enough blood to the rest of your body (heart failure)
•   As treatment following heart attack (myocardial infarction) complicated with heart failure.

2.   What you need to know before you take RAMIPRIL ACTAVIS Do not take RAMIPRIL ACTAVIS:

•   If you are allergic to ramipril, any other ACE inhibitor medicine or any of the other ingredients of this medicine (listed in section 6).
Signs of an allergic reaction may include a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
•   If you have ever had a serious allergic reaction called “angioedema”. The signs include itching, hives (urticaria), red marks on the hands, feet and throat, swelling of the throat and tongue, swelling around the eyes and lips, difficulty breathing and swallowing
•   If you are having dialysis or any other type of blood filtration. Depending on the machine that is used, RAMIPRIL ACTAVIS may not be suitable for you
•   If you have kidney problems where the blood supply to your kidney is reduced (renal artery stenosis)
•   During the last 6 months of pregnancy (see section below on “Pregnancy and breast-feeding”)
•   If your blood pressure is abnormally low or unstable. Your doctor will need to make this assessment.
•   If you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren
Do not take RAMIPRIL ACTAVIS if any of the above apply to you. If you are not sure, talk to your doctor before taking RAMIPRIL ACTAVIS.

Warnings and precautions

Talk to your doctor or pharmacist before taking RAMIPRIL ACTAVIS
•   If you have heart, liver or kidney problems
•   If you have lost a lot of body salts or fluids (through being sick (vomiting), having diarrhoea, sweating more than usual, being on a low salt diet, taking diuretics (water tablets) for a long time or having had dialysis)
•   If you are going to have treatment to reduce your allergy to bee or wasp stings (desensitization)
•   If you are going to receive an anaesthetic. This may be given for an operation or any dental work. You may need to stop your RAMIPRIL ACTAVIS treatment one day beforehand; ask your doctor for advice
•   If you have high amounts of potassium in your blood (shown in blood test results)
•   If you have collagen vascular disease such as scleroderma or systemic lupus erythematosus
•   You must tell your doctor if you think you are (or might become) pregnant. RAMIPRIL ACTAVIS is not recommended in the first 3 months of pregnancy and may cause serious harm to your baby after 3 months of pregnancy (see section below on “Pregnancy and breast-feeding”).
•   If you are taking any of the following medicines used to treat high blood pressure:
-   an angiotensin II receptor blocker (ARBs) (also known as sartans - for example valsartan, telmisartan, irbesartan), in particular if you have diabetes-related kidney problems.
-   aliskiren
•   If you are taking any of the following medicines, the risk of angioedema (rapid swelling under the skin in area such as the throat) is increased:
-   sirolimus, everolimus and other medicines belonging to the class of mTOR inhibitors (used to avoid rejection of transplanted organs)
Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g. potassium) in your blood at regular intervals.
See also information under the heading “Do not take RAMIPRIL ACTAVIS”

Children and adolescents

RAMIPRIL ACTAVIS is not recommended for use in children and adolescents below 18 years of age because safety and efficacy of RAMIPRIL ACTAVIS has not yet been established.
If any of the above apply to you (or you are not sure), talk to your doctor before taking RAMIPRIL ACTAVIS.

Other medicines and RAMIPRIL ACTAVIS

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because RAMIPRIL ACTAVIS can affect the way some other medicines work. Also some medicines can affect the way RAMIPRIL ACTAVIS works.
Please tell your doctor if you are taking any of the following medicines. They can make RAMIPRIL ACTAVIS work less well:
•   Medicines used to relieve pain and inflammation (e.g. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen or indometacin and aspirin)
•   Medicines used for the treatment of low blood pressure, shock, cardiac failure, asthma or allergies such as ephedrine, noradrenaline or adrenaline. Your doctor will need to check your blood pressure.
Please tell your doctor if you are taking any of the following medicines. They can increase the chance of getting side effects if you take them with RAMIPRIL ACTAVIS:
•   Medicines used to relieve pain and inflammation (e.g. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen or indometacin and aspirin)
•   Medicines for cancer (chemotherapy)
•   Medicines to stop the rejection of organs after a transplant such as ciclosporin
•   Diuretics (water tablets) such as furosemide
•   Medicines which can increase the amount of potassium in your blood such as spironolactone, triamterene, amiloride, potassium salts and other drugs which can increase the potassium in your body:
-   heparin (for thinning blood)
-   trimethoprim and co-trimoxazole also known as trimethoprim/sulfamethoxazole (for infections caused by bacteria)
•   Steroid medicines for inflammation such as prednisolone
•   Allopurinol (used to lower the uric acid in your blood)
•   Procainamide (for heart rhythm problems)
•   Temsirolimus (for cancer)
•   Medicines which are most often used to avoid rejection of transplanted organs (sirolimus, everolimus and other medicines belonging to the class of mTOR inhibitors). See section “Warnings and precautions”
Please tell your doctor if you are taking any of the following medicines. They may be affected by RAMIPRIL ACTAVIS:
•   Medicines for diabetes such as oral glucose lowering medicines and insulin. RAMIPRIL ACTAVIS may lower your blood sugar amounts. Check your blood sugar amounts closely while taking RAMIPRIL ACTAVIS
•   Lithium (for mental health problems). RAMIPRIL ACTAVIS may increase the amount of lithium in your blood. Your lithium amount will need to be closely checked by your doctor.
Your doctor may need to change your dose and/or to take other precautions:
•   If you are taking an angiotensin II receptor blocker (ARB) or aliskiren (see also information under the headings “Do not take RAMIPRIL ACTAVIS” and “Warnings and precautions”)
If any of the above apply to you (or you are not sure), talk to your doctor before taking RAMIPRIL ACTAVIS.

RAMIPRIL ACTAVIS with food and alcohol

Drinking alcohol with RAMIPRIL ACTAVIS may make you feel dizzy or light-headed. If you are concerned about how much you can drink while you are taking RAMIPRIL ACTAVIS, discuss this with your doctor as medicines used to reduce blood pressure and alcohol can have additive effects.
RAMIPRIL ACTAVIS may be taken with or without food.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
You must tell your doctor if you think you are (or might become) pregnant.
You should not take RAMIPRIL ACTAVIS in the first 12 weeks of pregnancy, and you must not take them at all after the 13 th week as their use during pregnancy may possibly be harmful to the baby.
If you become pregnant while on RAMIPRIL ACTAVIS, tell your doctor immediately. A switch to a suitable alternative treatment should be carried out in advance of a planned pregnancy.
Breast-feeding
You should not take RAMIPRIL ACTAVIS if you are breast-feeding.
Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

You may feel dizzy, while taking RAMIPRIL ACTAVIS. This is more likely to happen when you start taking RAMIPRIL ACTAVIS or start taking a higher dose. If this happens, do not drive or use any tools or machines.

RAMIPRIL ACTAVIS contains lactose.

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

3. How to take RAMIPRIL ACTAVIS

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.

Taking this medicine

•   Take this medicine by mouth at the same time of the day each day.
•   Swallow the tablets whole with liquid.
The tablets can be divided into equal doses.

How much to take

Treatment of high blood pressure
  The recommended starting dose is 1.25 mg or 2.5 mg once daily.
•   Your doctor will adjust the amount you take until your blood pressure is controlled.
•   The maximum dose is 10 mg once daily.
•   If you are already taking diuretics (water tablets), your doctor may stop or reduce the amount of the diuretic you take before beginning treatment with RAMIPRIL ACTAVIS.
To reduce the risk of you having a heart attack or stroke
  The recommended starting dose is 2.5 mg once daily.
•   Y our doctor may then decide to increase the amount you take.
•   The recommended dose is 10 mg once daily.
Treatment to reduce or delay the worsening of kidney problems
•   You may be started on a dose of 1.25 mg or 2.5 mg once daily.
•   Your doctor will adjust the amount you are taking.
•   The recommended dose is 5 mg or 10 mg once daily.
Treatment of heart failure
•   The recommended starting dose is 1.25 mg once daily.
•   Y our doctor will adj ust the amount you take.
•   The maximum dose is 10 mg daily. Two administrations per day are preferable.
Treatment after you have had a heart attack
  The recommended starting dose is 1.25 mg once daily to 2.5 mg twice daily.
•   Y our doctor will adj ust the amount you take.
•   The recommended dose is 10 mg daily. Two administrations per day are preferable.
Elderly
Your doctor will reduce the initial dose and adjust your treatment more slowly.

If you take more RAMIPRIL ACTAVIS than you should

Tell a doctor or go to the nearest hospital casualty department straight away. Do not drive to the hospital, get somebody else to take you or call for an ambulance. Take the medicine pack with you. This is so the doctor knows what you have taken.

If you forget to take RAMIPRIL ACTAVIS

If you miss a dose, take your normal dose when it is next due.
Do not take a double dose to make up for a forgotten tablet.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop taking RAMIPRIL ACTAVIS and see a doctor straight away, if you notice any of the following

serious side effects - you may need urgent medical treatment:
•   Swelling of the face, lips or throat which make it difficult to swallow or breathe, as well as itching and rashes. This could be a sign of a severe allergic reaction to RAMIPRIL ACTAVIS
•   Severe skin reactions including rash, ulcers in your mouth, worsening of a pre-existing skin disease, reddening, blistering or detachment of skin (such as Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiform).

Tell your doctor immediately if you experience:

•   Faster heart rate, uneven or forceful heartbeat (palpitations), chest pain, tightness in your chest or more serious problems including heart attack and stroke
•   Shortness of breath or a cough. These could be signs of lung problems
•   Bruising more easily, bleeding for longer than normal, any sign of bleeding (e.g. bleeding from the gums), purple spots blotching on the skin or getting infections more easily than usual, sore throat and fever, feeling tired, faint, dizzy or having pale skin. These can be signs of blood or bone marrow problems
•   Severe stomach pain which may reach through to your back. This could be a sign of pancreatitis (inflammation of the pancreas).
•   Fever, chills, tiredness, loss of appetite, stomach pain, feeling sick, yellowing of your skin or eyes (jaundice). These can be signs of liver problems such as hepatitis (inflammation of the liver) or liver damage.

Other side effects include:

Please tell your doctor if any of the following gets serious or lasts longer than a few days.
Common (may affect up to 1 in 10 people)
•   Headache or feeling tired
•   Feeling dizzy. This is more likely to happen when you start taking RAMIPRIL ACTAVIS or start taking a higher dose
•   Fainting, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly
•   Dry tickly cough, inflammation of your sinuses (sinusitis) or bronchitis, shortness of breath
•   Stomach or gut pain, diarrhoea, indigestion, feeling or being sick
•   Skin rash with or without raised area
•   Chest pain
•   Cramps or pain in your muscles
•   Blood tests showing more potassium than usual in your blood.
Uncommon (may affect up to 1 in 100 people)
•   Balance problems (vertigo)
•   Itching and unusual skin sensations such as numbness, tingling, pricking, burning or creeping on your skin (paraesthesia)
•   Loss or change in the way things taste
•   Sleep problems
•   Feeling depressed, anxious, more nervous than usual or restless
•   Blocked nose, difficulty breathing or worsening of asthma
•   A swelling in your gut called “intestinal angioedema” presenting with symptoms like abdominal pain, vomiting and diarrhoea
•   Heartburn, constipation or dry mouth
•   Passing more water (urine) than usual over the day
•   Sweating more than usual
•   Loss or decrease of appetite    (anorexia)
•   Increased or irregular heartbeats
•   Swollen arms and legs. This may be a sign of your body holding onto more water than usual
•   Flushing
•   Blurred vision
•   Pain in your joints
•   Fever
•   Sexual inability in men, reduced sexual desire in men or women
•   An increased number of certain white blood cells (eosinophilia) found during a blood test
•   Blood tests showing changes in the way your liver, pancreas or kidneys are working.
Rare (may affect up to 1 in 1,000 people)
•   Feeling shaky or confused
•   Red and swollen tongue
•   Severe flaking or peeling of the skin, itchy, lumpy rash
•   Nail problem (e.g. loosening or separation of a nail from its bed)
•   Skin rash or bruising
•   Blotches on your skin and cold extremities
•   Red, itchy, swollen or watery eyes
•   Disturbed hearing and ringing in your ears
•   Feeling weak
•   Blood tests showing a decrease in the number of red blood cells, white blood cells or platelets or in the amount of haemoglobin.
Very rare (may affect up to 1 in 10,000 people)
•   Being more sensitive to the sun than usual.
Not known (frequency cannot be estimated from the available data)
•   Concentrated urine (dark in colour), feel or are sick, have muscle cramps, confusion and fits which may be due to inappropriate ADH (anti-diuretic hormone) secretion. If you have these symptoms contact your doctor as soon as possible
•   Difficulty concentrating
•   Swollen mouth
•   Blood tests showing too few blood cells in    your blood
•   Blood tests showing less sodium than usual in your blood
•   Fingers and toes changing colour when you are cold and then tingling or feeling painful when you warm up (Raynaud's phenomenon)
•   Breast enlargement in men
•   Slowed or impaired reactions
•   Burning sensation
•   Change in the way things smell
•   Hair loss.
In children the frequency of the following is higher than in adults:
Common (may affect up to 1 in 10 people)
•   Increased heartbeat, blocked or running nose
•   Red, itchy, swollen or watery eyes
Uncommon (may affect up to 1 in 100 people)
•   Feeling shaky, itchy skin

Reporting of side effects

If you get any side effects, talk to your doctor or, pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via www.ravimiamet.ee . By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store RAMIPRIL ACTAVIS

Keep this medicine out of the sight and reach of children.
Do not store Ramipril Actavis above 25° C
Do not use this medicine after the expiry date which is stated on the carton and blister after “EXP”.
The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

6. Contents of the pack and other information What RAMIPRIL ACTAVIS contains

-   The active substance is ramipril. One tablet contains 1.25 mg, 2.5 mg, 5 mg or 10 mg ramipril.
-   The other ingredients are: Sodium hydrogen carbonate, lactose monohydrate, croscarmellose sodium, pregelatinised starch, sodium stearyl fumarate. Colourants: Tablets 2.5 mg/5 mg: Yellow iron oxide (E172). 5 mg tablets also contain red iron oxide (E172).

What RAMIPRIL ACTAVIS looks like and contents of the pack

Appearance
Tablets 2.5 mg: Yellow, capsule-shaped, flat tablets, scored on one side and on the edges. Tablets are marked “R2”.
Tablets 5 mg: Pink, capsule-shaped, flat tablets, scored on one side and on the edges. Tablets are marked “R3”.
Tablets 10 mg: White to whitish, capsule-shaped, flat tablets, scored on one side and on the edges. Tablets are marked “R4”.
Pack sizes
10, 14, 20, 28, 30, 42, 50, 90, 98 and 100 tablets.
Not all pack sizes may be marketed.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder Actavis Group PTC ehf Reykjavikurvegi 76-78 220 Hafnarfjördur Iceland
Manufacturer Actavis hf.
Reykjavikurvegur 78 IS-220 Hafnarfjöröur Iceland
Actavis Ltd
BLB016 Bulebel Industrial Estate
Zejtun ZTN 3000
Malta
Actavis Nordic A/S,
0rnegardsvej 16,
DK- 2820 Gentofte Denmark
Actavis (Balkanpharma) Dupnitsa AD 3 Samokovsko Shose Str.
Dupnitsa 2600 Bulgaria
For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder.
Teva Estonia representative
UAB Sicor Biotech Estonian Branch
Hallivanamehe 4
11317 Tallinn
Tel: +372 6610 801

This leaflet was last revised in May 2018.

This leaflet does not contain all the information about your medicine. If you have any questions or are not sure about anything, ask your doctor or pharmacist.
9





  Instruction, annotation source for medicine: State Agency of Medicines, Estonia




[*1]

DDD. Information source: WHO Collaborating Centre for Drug Statistics Methodology. Norwegian Institute of Public Health


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