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Attention: Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for treating a health problem or disease, or prescribing any medication. APTEKA.LV is not responsible for any damage to your health as the result of self treatment.


On 2019-May-27
BEROCCA-CA-drug/medicine -tablets aproximate price on "BEROCCA CA+MG EFFERV.TBL N10 " in Riga city, Latvia is:

  • 5.15€  5.76$  4.55£  371Rub  55.2SEK  22PLN  20.77₪ 

Check max allowed state price from goverment drugs agency webpage on ### "BEROCCA CA+MG EFFERV.TBL N10" ###

 ATC codeA11EC
 Active substances: Acidum Ascorbicum, Thiamini Hydrochloridum, Riboflavinum, Nicotinamidum, Acidum Pantothenicum, Pyridoxini Hydrochloridum, Cyanocobalaminum, Acidum Folicum, Biotinum, Calcium, Magnesium, Zincum

 Vendor, principal: Uab Bayer
 No prescription needed/Patient care products, dressings, gloves, medical devices,...


BEROCCA PLUS 15MG/+15MG/+10MG/+0.01MG/+500MG/+0.15MG/+50MG/+25MG/+100MG/+100MG/+0/+0 N10

Package leaflet: Information for the user

Berocca Plus, effervescent tablets

Vitamin B and C, calcium, magnesium and zinc preparation

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you.
-   Keep this leaflet. You may need to read it again.
-   Ask your pharmacist if you need more information or advice.
-   If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
-   You must talk to a doctor if you do not feel better or if you feel worse

What is in this leaflet

1.   What Berocca Plus effervescent tablets is and what it is used for
2.   What you need to know before you use Berocca Plus effervescent tablets
3.   How to use Berocca Plus effervescent tablets
4.   Possible side effects
5.   How to store Berocca Plus effervescent tablets
6.   Contents of the pack and other information

1. What Berocca Plus effervescent tablets is and what it is used for

Berocca Plus effervescent tablets contain as active ingredients all 8 B-vitamins, vitamin C, calcium, magnesium and zinc.
Berocca Plus effervescent tablets are used for treating a deficiency of and an increased requirement for vitamins B and C and zinc.
Vitamins and minerals are important nutrients for all living organisms. The human body cannot itself produce the vitamins and minerals it requires. In order to remain healthy and capable of functioning, the body must obtain these substances in sufficient quantities from the daily diet. Water-soluble vitamins such as B-vitamins and C are not stored in appreciable quantities in the body and the supply of these can therefore be inadequate in the elderly, pregnant and breast-feeding women, slimmers and patients suffering from certain chronic diseases, and in association with strenuous physical exercise and in prolonged stress or chronic heavy use of alcohol. The requirement for ascorbic acid (vitamin C) has been found to be increased in smokers and women taking contraceptive pills.
B vitamins
The B vitamins are involved in many different reactions in cell metabolism, including reactions in which substances which transmit the nerve impulses in the body are formed.
Vitamin C
Vitamin C (ascorbic acid) is an antioxidant which has an important function in the inactivation of free radicals. Vitamin C is also required for many enzyme functions and, for example, in the metabolism of cholesterol, bile acids and drugs. Vitamin C improves the uptake of iron from the intestine and affects the metabolism of folic acid and the function of the white blood cells. In addition, it improves the formation of connective tissue and is important for the development and function of the teeth, skeleton and capillaries.
Together with magnesium and vitamin B6, calcium is required in a number of complicated physiological processes, enzyme functions and transmission of nerve impulses.
Magnesium is involved in a number of processes in the body, such as the formation of proteins, fat metabolism, burning of sugar and cell respiration.
Zinc is an important trace element. It is a structural constituent of many proteins, hormones, neuropeptides and hormone receptors and is necessary for many enzyme functions.
Berocca Plus effervescent tablets do not contain any fat-soluble vitamins.

2. What you need to know before you use Berocca Plus effervescent tablets

Do not use Berocca Plus effervescent tablets:

-   if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).
-   if you suffer from known hypercalcaemia or hypercalciuria (too much calcium in the body or urine), kidney or urinary stones.
-   if you have raised quantities of oxalic acid in the urine or reduced renal function.

Warnings and precautions

Talk to your doctor or pharmacist before using Berocca Plus effervescent tablets.
-   Individuals with a deficiency of a certain enzyme (glucose-6-phosphate dehydrogenase) or haemochromatosis (disorder of iron storage), should use this product with precaution, because the product contains ascorbic acid i.e. vitamin C.
-   A Berocca Plus effervescent tablet contains about 10 % of the recommended daily allowance of calcium and about 30 % of the recommended daily allowance of magnesium. Thus, Berocca Plus contributes to the recommended daily intake of these elements, but is not sufficient as the only source of calcium and magnesium.
-   Berocca Plus effervescent tablets should only be used for the treatment of vitamin B12-deficiency if the cause is dietary. They should not be used to treat other forms of B12-deficiency (e.g. pernicious anemia or poor absorption of vitamin B12 due to diseases of the gut or pancreas).
-   One tablet contains the maximum daily dose of vitamin B6 (pyridoxine) for prophylactic use. The recommended daily dose (1 tablet) should not be exceeded.
-   As Berocca Plus can interfere with laboratory tests, inform your doctor if tests are planned.


Berocca Plus effervescent tablets are not recommended for children under 11 years of age.

Other medicines and Berocca Plus effervescent tablets

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.
-   Ascorbic acid (=vitamin C) can interfere with the determination of glucose in the urine or blood, so administration of vitamin C should be stopped several days before a glucose test is performed.
-   A pyridoxine dose of more than 5 mg abolishes the effect of levodopa used in the treatment of Parkinson’s desease. However, this does not happen if levodopa is taken together with carbidopa or benserazide.
-   If you use deferoxamine (e.g. to treat iron accumulation in your body) you should not take Berocca for the first month of therapy because Berocca Plus contains Vitamin C; using deferoxamine and vitamin C at the same time may affect your heart. Vitamin C may also interfere with the effect of cyclosporine, disulfiram and warfarin.
-   chloramphenicol can reduce the uptake of vitamin B12 from the digestive tract.
-   Folic acid can interfere with methotrexate (used to treat cancer e.g. leukemia).
-   If you are using diuretics, tell your doctor as it mayelevate levels of calcium, mangesium or zinc depending on the type of diuretic being used.
-   If you are taking antibiotics, levothyroxine (thyroid hormone), methyldopa (used to treat high blood pressure), mycophenolate mofetil (used by transplanted patients) or eltrombopag (used for decreased platelet count), make sure to take the product either 2 hours before or 4 hours after intake of the medicine to minimize interference.

Berocca Plus effervescent tablets with food

Iron: Vitamin C may enhance iron absorption, especially in individuals with iron deficiency.
Calcium, magnesium, and zinc: Since oxalic acid (found in spinach and rhubarb) and phytic acid (found in whole cereals) may inhibit calcium, magnesium, and zinc absorption, it is not recommended to take this product within two hours of eating foods containing high oxalic acid and phytic acid concentrations.

Pregnancy, breast-feeding and fertility

Pregnancy: There are no signs of harmful effects on the fetus/newborn at the recommended doses. However, Berocca Plus should be used during pregancy only when recommended by a doctor.
Breast feeding: The vitamins and minerals contained in Berocca Plus effervescent tablets pass into breast milk, but at recommended doses it is unlikely that this will cause side effects to the child.
The labeled dose should not be exceeded since chronic overdose might be harmful to the fetus and neonate.
Fertility: There is no evidence suggesting that the product cause reproductive effects.

Driving and using machines

Berocca Plus effervescent tablets do not affect the ability to drive or use machines.

Berocca Plus effervescent tablets contains vitamin B2

After taking Berocca Plus effervescent tablets, the urine has an abnormal yellow colour. This is due to the vitamin B2 that is included in the product. This is completely harmless.

Berocca Plus effervescent tablets contains sodium

One Berocca Plus effervescent tablet contains 272 mg sodium. To be taken into consideration by patients on a controlled sodium diet.

Berocca Plus effervescent tablets contains sweeteners

Berocca Plus effervescent tablets are sweetened with aspartame E951, mannitol E421and acesulfam K. Aspartame E951 is a source of phenylalanine which may be harmful for people with phenylketonuria. Patient suffering from phenylketonuria should not use the product.
This product contains a small quantity of sucrose from the colourant.
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
Diabetics can take Berocca Plus effervescent tablets.

3. How to use Berocca Plus effervescent tablets

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose for adults and children over 11 years of age is 1 effervescent tablet daily.
The effervescent tablet should be dissolved in a glass of water.
The recommended daily dosage must not be exceeded.

If you use more Berocca Plus effervescent tablets than you should

- immediately contact a doctor, pharmacist, hospital emergency room or Poison Information Center (to be completed nationally), if you or someone else (e.g. a small child) have taken an overdose of Berocca Plus.
There is no evidence that this product can lead to overdose when taken as labelled. Symptoms of overdose may include confusion and gastrointestinal disturbance, such as constipation, diarrhoea, nausea and vomiting. High doses of vitamin B6 (200 to 6000 mg/day for months or years) may cause symptoms of neuropathy, such as pain and prickling of the skin, specially in hands and feet.
If you have any further questions on the use of this product, ask your pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
The active substances in Berocca Plus effervescent tablets are substances found naturally in the human body and their use usually does not cause any side effects.
Reported side effects include diarrhea, nausea, vomiting, constipation, and gastrointestinal and abdominal pains. Headache, dizziness, insomnia, nervousness may occur.
Allergic reactions, anaphylactic reactions and shock have also been reported.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly www.ravimiamet.ee . By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Berocca Plus effervescent tablets

Store Berocca Plus effervescent tablets below 25°C and keep the tube tightly closed, since effervescent tablets disintegrate if they are exposed to moisture.
Keep this medicine out of the sight and reach of children.
Do not allow children to play with the empty packaging as they could swallow the desiccant.
Do not use this medicine after the expiry date which is stated on the blister and carton after EXP. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

6. Contents of the pack and other information What Berocca Plus effervescent tablets contains

The active substances are:
Ascorbic acid
Vitamin C
500 mg
Thiamine hydrochloride
Vitamin B1
15 mg
Vitamin B2
15 mg
Vitamin B3
50 mg
Calcium pantothenate 1 equivalent to pantothenic acid
Vitamin B5
23 mg
Pyridoxine hydrochloride
Vitamin B6
10 mg
Vitamin B12
10 mcg

150 mcg
Folic acid

400 mcg
Calcium carbonate 1

244 mg
Magnesium carbonate 2 Magnesium sulphate dihydrate Zinc citrate trihydrate 3
195 mg 328 mg 32 mg
1   total calcium 100 mg
2   total magnesium 100 mg
3   total zinc 10 mg
*added as cyanocobalamin 0.1% WS - The other ingredients are:
Anhydrous citric acid, sodium hydrogen carbonate, sodium chloride, acesulfame K (20 mg), aspartame E951 (25 mg), mannitol E421 (276 mg), polysorbate 60, anhydrous sodium carbonate, the colorants beta-carotene 1% SD and beetroot extract, and the flavour additive Plus flavour PERMASEAL 10401-71. Cyanocobalamine 0.1% WS contains the excipients sodium citrate, anhydrous citric acid and maltodextrin. Beta-carotene 1% SD contains beta-carotene, sodium ascorbate, alpha-tocopherol, acacia gum, coconut oil, sucrose and maltodextrin.
The Plus flavour PERMASEAL 10401-71 contains flavourings, natural flavourings, maltodextrin and gum Arabic.

What Berocca Plus effervescent tablets looks like and contents of the pack

The Berocca Plus effervescent tablet is of cylindrical shape (diameter 25 mm), smooth surface, and of spotted light-Plus colour. When a Berocca Plus effervescent tablet is dissolved in a glass of water it produces a pleasant-tasting drink that derives its colour from natural carotenoids, beetroot extract and vitamin B2.
Berocca Plus effervescent tablets are packed in plastic tubes of 10 and 15 tablets and are available in packs of 10, 15, 20, 30, 45 and 60 tablets. Berocca Plus effervescent tablets are also available in aluminium foil strip packs of 1 tablet.
Not all pack sizes may be marketed.

Marketing Authorisation Holder and Manufacturer

Marketing Authorisation Holder:
UAB Bayer Sporto 18 LT-09238 Vilnius Lithuania
Delpharm Gaillard 33, Rue de l'Industrie 74240 Gaillard France

This leaflet was last revised in 2016-02


  Instruction, annotation source for medicine: State Agency of Medicines, Estonia


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