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NITROGLYCERIN 0.5MG TBL N40

Attention: Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for treating a health problem or disease, or prescribing any medication. iDrugs24.com is not responsible for any damage to your health as the result of self treatment.

# On 2024-Mar-29
NITROGLYCERIN-drug/medicine -tablets aproximate price on "NITROGLYCERIN 0.5MG TBL N40" in Riga city, Latvia is:
  • 3.25€  3.51$  2.78£  375Rub  37.5SEK  14PLN  12.93₪ 

NITROGLYCERIN 0.5 MG TBL N40


Check max allowed state price from goverment drugs agency webpage on ### "NITROGLYCERIN 0.5MG TBL N40" ###

ATC codeC01DA02 

Active substances: Nitroglycerolum

 


Vendor, principal: Nycomed Danmark As
No prescription needed/Patient care products, dressings, gloves, medical devices,...

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NITROGLYCERIN Nycomed 0,5 mg tabletes, 40 gab.

 .

NITROGLYCERIN NYCOMED 0.5MG N25

Package leaflet: Information for the user Nitroglycerin Nycomed, 0.5 mg sublingual tablets

Glyceryl trinitrate

Read all of this leaflet carefully before you start using this medicine because it contains important information for you.

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.
-   Keep this leaflet. You may need to read it again.
-   Ask your pharmacist if you need more information or advice.
-   You must talk to a doctor if you do not feel better or if you feel worse.
-   If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

What is in this leaflet

1.   What Nitroglycerin Nycomed is and what it is used for
2.   What you need to know before you take Nitroglycerin Nycomed
3.   How to take Nitroglycerin Nycomed
4.   Possible side effects
5.   How to store Nitroglycerin Nycomed
6.   Contents of the pack and other information

1. What Nitroglycerin Nycomed is and what it is used for

One tablet contains 0.5 mg of glyceryl trinitrate, which is used for vasodilatation in the case of heart diseases.
Nitroglycerin Nycomed is used for the prophylaxis and treatment of angina.

2. What you need to know before you take Nitroglycerin Nycomed Do not take Nitroglycerin Nycomed:

-   if you are allergic to glyceryl trinitrate or any of the other ingredients of this medicine (listed in section 6);
-   if you have very low blood pressure;
-   if you have anaemia;
-   if you have congestive heart failure, fluid (blood) build-up in pericardial cavities or myocardial infarction;
-   if you have elevated pressure in the intra-cranial cavity, craniocerebral trauma or cerebral haemorrhage;
-   if you have angle-closure glaucoma (eye disease);
-   if you have severe liver impairment;
-   if you are using sildenafil (Viagra), vardenafil (Levitra) or tadalafil (Cialis) (medicines used in the case of erectile dysfunction).

Warnings and precautions

-   if you have glaucoma, as the use of nitrates may increase intraocular pressure;
-   if you have severe renal impairment;
-   if you have decreased function of the thyroid gland (hypothyroidism).
Nitroglycerin Nycomed may cause a drop in blood pressure even in the case of small doses. Therefore, it is advisable to sit or lie down after taking the tablet to avoid potential fainting.
When using nitrates, you may develop tolerance (gradual decrease in the effect of the medicine) to their effect. To avoid this, use as small a dose of nitrates as possible and try to keep a 10-12-hour interval between administration times. Using the smallest possible dose, keeping an interval between administration times or intermittent treatment with other medicines that dilate coronary arteries help decrease the risk of tolerance.
Angina treatment with nitrates should be stopped by gradual reduction of doses in order to prevent withdrawal symptoms.
Talk to your doctor or pharmacist before using Nitroglycerin Nycomed.

Other medicines and Nitroglycerin Nycomed

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Take special care when using Nitroglycerin Nycomed:
-   if you are using medicines with vasodilatory effect or medicines which lower blood pressure.
These medicines may increase the blood-pressure-lowering effect of glyceryl trinitrate.
-   if you are using sildenafil (e.g. Viagra), vardenafil (e.g. Levitra) or tadalafil (e.g. Cialis)
(medicines used in the case of erectile dysfunction), as they may cause a significant drop in blood pressure along with a risk of severe side effects, such as fainting and myocardial infarction. Concomitant use of glyceryl trinitrate with sildenafil, vardenafil and tadalafil is contraindicated.
-   if you are using medicines that cause dryness of the mouth as a side effect (e.g. tricyclic antidepressants). These medicines may reduce the effectiveness of glyceryl trinitrate sublingual tablets, as they may dissolve slower as a result.
-   if you are using acetylsalicylic acid, as it may strengthen the effect of glyceryl trinitrate;
-   if you are using heparin (anticoagulant). Glyceryl trinitrate may reduce the anticoagulant effect of heparin.
-   if you are using dihydroergotamine (DHE), as it poses a risk of DHE poisoning (peripheral tissue oxygen deficiency, abnormal sensation, nausea and vomiting);
-   if you are using alteplase (a blood-clot dissolving medicine), as it may cause rapid breakdown of alteplase in the body. As a result, alteplase may not be as effective in dissolving blood clots.

Nitroglycerin Nycomed with food and drink

Concomitant use of alcohol may cause a significant drop in blood pressure and collapse.

Pregnancy, breast-feeding and fertility

If you are pregnant or breast-feeding ,think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
Data on the use of glyceryl trinitrate during pregnancy have not indicated side effects on the pregnancy or the health of the foetus/infant.
Breast-feeding
No data is available but no side effects on humans have been proven.

Driving and using machines

Take special care when driving or using machines. Glyceryl trinitrate may reduce reaction speed, especially if the therapeutic dose has been increased or if alcohol has been used concomitantly with the medicine.

Nitroglycerin Nycomed contains lactose monohydrate

This medicine contains lactose monohydrate as an excipient. If you have been told by your doctor that you have intolerance to some sugars, talk to your doctor before taking this medicine.

3. How to take Nitroglycerin Nycomed

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
One 0.5 mg tablet is placed under the tongue or cheek pocket (between the cheek and gum) when first symptoms of angina occur or before an activity or load that may induce angina. If necessary, repeat the dose in 5 minutes. If the pain persists after taking three tablets within 15 minutes, talk to your doctor.
Sit or lie down after taking the tablet in order to prevent potential fainting.
The effect occurs 1-3 minutes after sublingual administration. The effect lasts for 30-60 minutes.

Use in children

Nitroglycerin Nycomed may not be used in children younger than 15 years without a doctor’s prescription.
Elderly
Elderly patients may be more sensitive to the blood-pressure-lowering effect of nitrates. In addition, the elderly are more likely to suffer from age-related loss of renal function; therefore, special care must be taken when administering nitrates to the elderly.
If you feel that the effect of Nitroglycerin Nycomed is too strong or too weak, talk to your doctor or pharmacist.

If you take more Nitroglycerin Nycomed than you should

If you take more tablets than you should or if a child has accidentally ingested the medicine, immediately talk to your doctor or the emergency department of the nearest hospital.
Overdose symptoms of glyceryl trinitrate include a drop in blood pressure, rapid heart beat, warm and red skin, headache, balance disorders, heart palpitations, visual disturbances, dizziness, fainting, nausea, vomiting, loss of appetite, shortness of breath and shallow breathing, slow heart rate, confusion, moderate fever, paralysis, elevated intracranial pressure with confusion and neurological withdrawal symptoms.
Overdose treatment in the case of ingesting nitrates is symptomatic and supportive. Induce vomiting or carry out a gastric lavage and administer active charcoal. Low blood pressure and tachycardia may be treated by lifting legs higher than the head. Adrenalin is generally not effective in the treatment of a severe drop in blood pressure caused by a glyceryl trinitrate overdose.
It is necessary to monitor blood gases and methaemoglobin concentration in arterial blood.
Oxygen treatment and methylene blue are used in the case of methemoglobinemia.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Side effects are classified based on incidence as follows:
Common:   may affect less than 1 user in    10, but more than 1 user in 100
Uncommon:   may affect less than 1 user in    100, but more than 1 user in 1,000
Rare:   may affect less than 1 user in    1,000, but more than 1 user in 10,000
Very rare:   may affect less than 1 user in    10,000 and single cases.
Blood and lymphatic system disorders:
Very rare:   presence of methemoglobin in the blood
Cardiac disorders:
Common:   low blood pressure that may result in increased heart rate, nausea and fainting
Rare:   slow heart rate
Very rare:   paradoxical angina attack
Gastrointestinal disorders:
Uncommon:   burning sensation in the    mouth
Skin and subcutaneous tissue disorders:
Common:   flushing of the face
General disorders and administration site reactions:
Common:   headache (in about 50% of patients at the beginning of treatment, recedes in a
few weeks); in most patients taking glyceryl trinitrate on a regular basis, weakness occurs in 24 hours. Development of tolerance may be prevented with a 10-12-hour interval between administration times. Dizziness, cyanosis (blueness of the skin) in rare cases.
In single cases, exfoliative dermatitis (skin disease characterised by extensive scaling) has occurred.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects
not listed in this leaflet. You can also report side effects directly via www.ravimiamet.ee. By reporting
side effects you can help provide more information on the safety of this medicine.

5. How to store Nitroglycerin Nycomed

Keep this medicine out of the sight and reach of children.
Do not store at a temperature higher than 25 °C. Keep the bottle tightly sealed.
Do not use this medicine after the expiry date which is stated on the bottle. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

6. Contents of the pack and other information What Nitroglycerin Nycomed contains

-   The active substance is glyceryl trinitrate. One sublingual tablet contains 0.5 mg of glyceryl trinitrate.
-   The other ingredients are magnesium stearate, talc, agar, microcrystalline cellulose and lactose monohydrate.

What Nitroglycerin Nycomed looks like and contents of the pack

Nitroglycerin Nycomed tablets are white, smooth and with inclined edges.
Nitroglycerin Nycomed tablets are packaged in a glass jar and a cardboard carton. The package contains 40 tablets.

Marketing Authorisation Holder

Takeda Pharma AS
Jaama 55B
63308 Pölva
Estonia

Manufacturer

Takeda Pharma Sp. z o.o.
Plant Lyszkowice 12, Ksi^stwa Lowickiego Str. 99-420 Lyszkowice Poland
This leaflet was last revised in January 2016.
5





  Instruction, annotation source for medicine: State Agency of Medicines, Estonia





• Medicaments images are for illustrative purposes only and may differ from the actual product.


[*1]

DDD. Information source: WHO Collaborating Centre for Drug Statistics Methodology. Norwegian Institute of Public Health


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